Ask Osler Priority Sheet Cardiac - Priority Sheet

When to Hold Digoxin NCLEX Priority Sheet

Digoxin hold questions test apical pulse, toxicity symptoms, potassium, renal clearance, and whether the nurse recognizes the risk before giving the dose.

Study aid - not medical advice. Not a clinical decision tool. For NCLEX pharmacology review only.

Priority 1

What to do first

1. Count the apical pulse for 1 full minute before administration.
2. Compare the pulse with the ordered hold parameter or institutional protocol.
3. Check for nausea, vomiting, anorexia, visual halos, confusion, and new arrhythmias.

Safety

Hold If

Notify the provider and follow institutional protocol for adult apical pulse <60 bpm, suspected toxicity, new dysrhythmia, visual changes, severe GI symptoms, or marked electrolyte abnormality.

Do not independently treat bradycardia or potassium changes. Anticipate ordered evaluation and correction.

Monitoring

Labs to Watch

Digoxin level: NCLEX commonly uses 0.5-2.0 ng/mL. Heart failure targets may be lower in current practice.

Watch K+, Mg++, BUN, creatinine, and renal function trends. Hypokalemia increases toxicity risk even when digoxin level looks therapeutic.

Review Details

NCLEX Review Notes

Key Signs
Early classic clue: anorexia, then nausea and vomiting.

Visual: yellow-green halos, blurred vision, photophobia.

Cardiac: bradycardia, AV block, PVCs, or other new dysrhythmias.
NCLEX Trap
Trap: the digoxin level is 0.9 ng/mL, but K+ is 3.1 mEq/L and the patient has nausea.

Safer answer: do not call the drug automatically safe because the digoxin level is in range. Recognize hypokalemia plus symptoms, hold per protocol, and notify the provider.
Related Pattern
Digoxin + loop diuretic: furosemide can lower potassium, which increases digoxin toxicity risk.

Digoxin + renal impairment: reduced clearance raises toxicity risk. NCLEX often hides the clue in creatinine or older adult status.
Mini Quiz
Question: A patient is due for digoxin. Apical pulse is 54 and the patient reports blurred yellow vision. What should the nurse do first?

Answer: hold the dose per protocol, assess for toxicity, and notify the provider.
References
Saunders Comprehensive Review for the NCLEX-RN Examination; Davis's Drug Guide for Nurses; DailyMed digoxin labeling; 2022 ACC/AHA/HFSA heart failure guideline.