Priority 1
What to do first
1. Count the apical pulse for 1 full minute before administration.
2. Compare the pulse with the ordered hold parameter or institutional protocol.
3. Check for nausea, vomiting, anorexia, visual halos, confusion, and new arrhythmias.
Safety
Hold If
Notify the provider and follow institutional protocol for adult apical pulse <60 bpm, suspected toxicity, new dysrhythmia, visual changes, severe GI symptoms, or marked electrolyte abnormality.
Do not independently treat bradycardia or potassium changes. Anticipate ordered evaluation and correction.
Monitoring
Labs to Watch
Digoxin level: NCLEX commonly uses 0.5-2.0 ng/mL. Heart failure targets may be lower in current practice.
Watch K+, Mg++, BUN, creatinine, and renal function trends. Hypokalemia increases toxicity risk even when digoxin level looks therapeutic.
Review Details
NCLEX Review Notes
Key Signs
Early classic clue: anorexia, then nausea and vomiting.
Visual: yellow-green halos, blurred vision, photophobia.
Cardiac: bradycardia, AV block, PVCs, or other new dysrhythmias.
NCLEX Trap
Trap: the digoxin level is 0.9 ng/mL, but K+ is 3.1 mEq/L and the patient has nausea.
Safer answer: do not call the drug automatically safe because the digoxin level is in range. Recognize hypokalemia plus symptoms, hold per protocol, and notify the provider.
Related Pattern
Digoxin + loop diuretic: furosemide can lower potassium, which increases digoxin toxicity risk.
Digoxin + renal impairment: reduced clearance raises toxicity risk. NCLEX often hides the clue in creatinine or older adult status.
Mini Quiz
Question: A patient is due for digoxin. Apical pulse is 54 and the patient reports blurred yellow vision. What should the nurse do first?
Answer: hold the dose per protocol, assess for toxicity, and notify the provider.
References
Saunders Comprehensive Review for the NCLEX-RN Examination; Davis's Drug Guide for Nurses; DailyMed digoxin labeling; 2022 ACC/AHA/HFSA heart failure guideline.